Bullous pemphigoid in a patient with psoriasis after mRNA COVID‐19 vaccination

PUVA induced bullous pemphigoid in a patient with psoriasis.

A bullous eruption in a patient with psoriasis was first described by Bloom in 1929 (as cited by Weber) (1). Since then there have been several reports of bullous pemphigoid occurring during the treatment of psoriasis, especially after ultraviolet (UV) B exposure. Comorbidity of these two diseases without treatment has also been reported (2,3). Psoriasis is one of the most common chronic inflam...

Remission of bullous pemphigoid after rituximab treatment in a psoriasis patient on regular low-dose methotrexate.

Bullous colon lesions in a patient with bullous pemphigoid.

Bullous pemphigoid (BP) is a subepidermal blistering disease associated with circulating autoantibodies directed against structural components of hemidesmosomes, adhesion complexes promoting epithelial-stromal adhesion in human skin, and other complex epithelia. Two hemidesmosomal proteins, the BP antigen 180 (BP180) and the BP antigen 230 (BP230), have been shown to be the target antigens.1,2 ...

Infantile Bullous Pemphigoid Following Vaccination.

BACKGROUND Post-vaccination infantile bullous pemphigod is a rare presentation. CASE CHARACTERISTICS A 2-month-old girl presented with widespread bullae, erosions, necrotic and targetoid lesions over body and mucosae after vaccination. Histology and direct immunofluorescence (DIF) were consistent with bullous pemphigoid. INTERVENTION Clinical remission with oral steroids and no recurrence w...

PUVA-induced Bullous Pemphigoid in Psoriasis.

The association between psoriasis vulgaris and bullous pemphigoid is due to the still unclear autoimmune process. The common disease site is the dermo-epidermal junction or basal membrane zone (BMZ), with specific alterations for both diseases. Photochemotherapy (PUVA) is one of the therapeutic modalities for psoriasis and can trigger production of autoantibodies against antigens in the BMZ in ...